Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.54 |
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12489315 | 0.98 | LMNA (0.55) | ALDH1A1MAPTLMNAALOX12NPSR1 | |
| SCHEMBL15543926 | 0.85 | MAPT (0.71) | ALDH1A1MAPTNPSR1KMT2AHTT | |
| SCHEMBL23612067 | 0.83 | MAPT (0.47) | ALDH1A1MAPTLMNAALOX12NPSR1 | |
| SCHEMBL30021064 | 0.83 | MAPT (0.47) | ALDH1A1MAPTLMNAALOX12NPSR1 | |
| SCHEMBL31167860 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAALOX12NPSR1 | |
| SCHEMBL31167872 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAALOX12NPSR1 | |
| SCHEMBL3665818 | 0.80 | MAPT (0.76) | ALDH1A1MAPTLMNAALOX12NPSR1 | |
| SCHEMBL31167758 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNAALOX12NPSR1 | |
| SCHEMBL26089817 | 0.78 | MAPT (0.52) | ALDH1A1MAPTLMNAALOX12NPSR1 | |
| SCHEMBL15012807 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNAALOX12NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180111927-A1 | HETEROCYCLIC-IMIDAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI HUILUN LIFE SCIENCE & TECHNOLOGY CO., LTD (CN) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111927-A1 | HETEROCYCLIC-IMIDAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | PARP1, PARP8, PARP11 | ALDH1A1 316/4885MAPT 2546/4885LMNA 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.