SCHEMBL2008974

SCHEMBL2008974

CCOC(=O)COC1CCNCC1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.41
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
ITGB3 P05106 4/20 0.39
ITGA2B P08514 4/20 0.39
TRPA1 O75762 1/20 0.36
ALDH1A1 P00352 1/20 0.36
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
POLB P06746 2/20 0.34
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL25246154 0.98 KMT2A (0.40) KMT2AMGAMGAASIMGAM2
SCHEMBL4696166 0.90 MAPT (0.39) KMT2AMGAMGAASIMGAM2
SCHEMBL12571540 0.90 MAPT (0.39) KMT2AMGAMGAASIMGAM2
SCHEMBL4407526 0.90 MAPT (0.39) KMT2AMGAMGAASIMGAM2
Hydrochloric Acid SCHEMBL29927379 0.88 MAPT (0.41) KMT2AMGAMGAASIMGAM2
Hydrochloric Acid SCHEMBL23294651 0.88 MAPT (0.41) KMT2AMGAMGAASIMGAM2
SCHEMBL27359045 0.85 KMT2A (0.36) KMT2AMGAMGAASIMGAM2
SCHEMBL12773729 0.85 CHRM1 (0.41) KMT2AITGB3ITGA2BALDH1A1SLC6A2
SCHEMBL23249976 0.84 EPHX2 (0.36) KMT2AMGAMGAASIMGAM2
SCHEMBL26466091 0.84 GABRP (0.33) ITGB3ITGA2BSLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250032454-A1 KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE IMAGO BIOSCIENCES, INC. (US) 2025-01-30 US disclosed
EP-4419504-A1 KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE Imago Biosciences Inc. (US) 2024-08-28 EP disclosed
CN-112384509-B Furin inhibitors 葛兰素史密斯克莱知识产权发展有限公司 2024-04-30 CN disclosed
CN-117510504-A Protein kinase degradation agent, medicine and application 深圳市新樾生物科技有限公司 2024-02-06 CN disclosed
EP-3790871-B1 FURIN INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2024-01-24 EP disclosed
EP-3790871-B1 FURIN INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2024-01-24 EP disclosed
WO-2024001839-A1 HETEROAROMATIC RING COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2024-01-04 WO disclosed
US-11773078-B2 Furin inhibitors GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2023-10-03 US disclosed
US-11773078-B2 Furin inhibitors GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2023-10-03 US disclosed
US-11773078-B2 Furin inhibitors GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2023-10-03 US disclosed
EP-0741133-A2 Adhesion receptor antagonists MERCK PATENT GmbH (DE) 1996-11-06 EP disclosed
US-5545658-A FOR TREATMENT OR PROPHYLAXIS OF ILLNESSES WHICH ARE CAUSED BY THE BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELETS AND BY BLOOD PLATELET AGGREGATION AND CELL-CELL ADHESION HOFFMAN-LA ROCHE INC. (US) 1996-08-13 US disclosed
US-5532255-A Adhesion receptor antagonists MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1996-07-02 US disclosed
EP-0632019-A1 Acylureas ZENECA LIMITED (GB) 1995-01-04 EP disclosed
US-5378712-A Antithrombosis Hoffmann-La Roche Inc (US) 1995-01-03 US disclosed
US-4039731-A PHOTODEGRADABLE POLYOLEFINS CONTAINING NITROHALOALKANES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1977-08-02 US disclosed
US-4020249-A Photodegradable polyolefins containing haloalkyl- or halobenzene-sulfonyl halides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1977-04-26 US disclosed
US-4018922-A NEUROLEPTICS, ANALGESICS, SPASMOLYTICS, AND ANTIHISTAMINES ROUSSEL-UCLAF (FR) 1977-04-19 US disclosed
US-4017666-A POLLUTION CONTROL THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1977-04-12 US disclosed
US-3968096-A Photodegradable polyolefins containing an halogenated nitrile THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11773078-B2 Furin inhibitors FURIN, TGFB1, PCSK7 KMT2A 4129/4885MGAM 2580/4885GAA 405/4885
US-20250032454-A1 KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE KDM1B, KDM1A, KDM2A KMT2A 14/4885MGAM 4221/4885GAA 1725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.