SCHEMBL20089852

SCHEMBL20089852

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4c(-c5cccc6ccccc56)c5ccccc5c5ccccc45)cc3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
NFKB1 P19838 1/20 0.39
MAPK1 P28482 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
ATM Q13315 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MCL1 Q07820 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20089877 0.94 CA12 (0.45) CA12CA1CA2CA9KDM4E
SCHEMBL20089853 0.92 CA12 (0.43) CA12CA1CA2CA9KDM4E
SCHEMBL23820625 0.92 CA12 (0.43) CA12CA1CA2CA9KDM4E
SCHEMBL20089894 0.91 MCL1 (0.39) CA12CA1CA2CA9KDM4E
SCHEMBL22671291 0.91 CA12 (0.42) CA12CA1CA2CA9KDM4E
SCHEMBL13820584 0.90 MCL1 (0.35) CA12CA1CA2CA9KDM4E
SCHEMBL10063892 0.89 CA12 (0.40) CA12CA1CA2CA9KDM4E
SCHEMBL13820301 0.88 MCL1 (0.36) CA12CA1CA2CA9KDM4E
SCHEMBL20089944 0.88 CA12 (0.47) CA12CA1CA2CA9KDM4E
SCHEMBL20089939 0.88 CA12 (0.47) CA12CA1CA2CA9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240023429-A1 MONOAMINE COMPOUND AND LIGHT EMITTING ELEMENT INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-18 US disclosed
US-20240023429-A1 MONOAMINE COMPOUND AND LIGHT EMITTING ELEMENT INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-18 US disclosed
US-11575086-B2 Monoamine compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-07 US disclosed
US-20210135110-A1 MONOAMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-05-06 US disclosed
US-10923663-B2 Monoamine compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-02-16 US disclosed
US-20180114907-A1 MONOAMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-04-26 US disclosed
US-20180114907-A1 MONOAMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10923663-B2 Monoamine compound and organic electroluminescence device including the same MAOA, COMT, MAOB CA12 3685/4885CA1 2437/4885CA2 3645/4885
US-20210135110-A1 MONOAMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME MAOA, COMT, MAOB CA12 3685/4885CA1 2437/4885CA2 3645/4885
US-20180114907-A1 MONOAMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME MAOA, COMT, MAOB CA12 3685/4885CA1 2437/4885CA2 3645/4885
US-20240023429-A1 MONOAMINE COMPOUND AND LIGHT EMITTING ELEMENT INCLUDING THE SAME MAOA, TPH1, MAOB CA12 2156/4885CA1 1092/4885CA2 3295/4885
US-11575086-B2 Monoamine compound and organic electroluminescence device including the same MAOA, COMT, MAOB CA12 3685/4885CA1 2437/4885CA2 3645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.