Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | AKT1 | P31749 | 2/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | CDC25A | P30304 | 1/20 | 0.62 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | PRKCG | P05129 | 1/20 | 0.51 |
| ▸ | PRKCB | P05771 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 1/20 | 0.51 |
| ▸ | PRKCH | P24723 | 1/20 | 0.51 |
| ▸ | PRKCI | P41743 | 1/20 | 0.51 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.51 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.51 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.51 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19689041 | 0.85 | LMNA (0.59) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL9067683 | 0.83 | LMNA (0.54) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL906188 | 0.83 | LMNA (0.68) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL26756555 | 0.83 | LMNA (0.73) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL4972574 | 0.83 | LMNA (0.86) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL8561854 | 0.83 | LMNA (0.61) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL1853865 | 0.82 | SMN1; SMN2 (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL8588037 | 0.82 | LMNA (0.61) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL19734900 | 0.80 | SMN1; SMN2 (0.60) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL8911167 | 0.79 | LMNA (0.58) | LMNAAKT1ESR1ADORA3CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230251257-A1 | SUBSTRATE FOR IMMOBILIZING SUBSTANCE, AND USE THEREOF | R-NANOBIO CO. LTD. (JP) | 2023-08-10 | — | — | US | disclosed |
| US-20180113237-A1 | AMPHIPHILIC BRANCHED POLYDIORGANOSILOXANE MACROMERS | ALCON INC. (CH) | 2018-04-26 | — | — | US | disclosed |