Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | AKT1 | P31749 | 2/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | CDC25A | P30304 | 1/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483641 | 0.88 | LMNA (0.54) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL19689041 | 0.84 | LMNA (0.59) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL6130431 | 0.83 | SMN1; SMN2 (0.50) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL906188 | 0.83 | LMNA (0.68) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL4972574 | 0.83 | LMNA (0.86) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL26756555 | 0.83 | LMNA (0.73) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL8911167 | 0.83 | LMNA (0.58) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL20090040 | 0.83 | LMNA (0.62) | LMNAAKT1ESR1ADORA3CDC25A | |
| Phosphocholine SCHEMBL18192302 | 0.81 | LMNA (0.55) | LMNAAKT1ESR1ADORA3CDC25A | |
| Phosphocholine SCHEMBL9447039 | 0.81 | LMNA (0.55) | LMNAAKT1ESR1ADORA3CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5851548-A | Liposomes containing cationic lipids and vitamin D | GEN-PROBE INCORPORATED (US) | 1998-12-22 | — | — | US | disclosed |
| US-5759519-A | Method for the intracellular delivery of biomolecules using thiocationic lipids | GEN-PROBE INCORPORATED (US) | 1998-06-02 | — | — | US | disclosed |
| US-5756352-A | CATIONIC CHARGES FOR LIPIDS USED IN DIAGNOSIS | GEN-PROBE INCORPORATED (US) | 1998-05-26 | — | — | US | disclosed |
| US-5739271-A | DRUG DELIVERY OF OLIGONUCLEOTIDES, NUCLEIC ACIDS, PEPTIDES, IMAGES, AND PROTEINS | GEN-PROBE INCORPORATED (US) | 1998-04-14 | — | — | US | disclosed |
| US-5711964-A | CELLULAR METABOLISM AND CATIONIC LIPIDS | UNITED STATES OF AMERICA (US) | 1998-01-27 | — | — | US | disclosed |
| WO-1996040627-A2 | THIOCATIONIC LIPIDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | GEN-PROBE INCORPORATED (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0747351-A2 | Thiocationic lipids, pharmaceutical compositions and methods of use thereof | GEN-PROBE INCORPORATED (US) | 1996-12-11 | — | — | EP | disclosed |