Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL2009106

N.N.Nc1ccc(Oc2ccc(Oc3ccc(N)cc3)cc2)cc1

nearest known ligand 0.93

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.93
TDP1 Q9NUW8 4/20 0.93
CYP3A4 P08684 2/20 0.93
TSHR P16473 1/20 0.93
MAOA P21397 2/20 0.74
MAPT P10636 6/20 0.70
TEAD4 Q15561 1/20 0.70
MAOB P27338 1/20 0.70
MEN1 O00255 4/20 0.67
KMT2A Q03164 4/20 0.67
SMN1; SMN2 Q16637 3/20 0.67
POLB P06746 1/20 0.67
MITF O75030 1/20 0.67
GAA P10253 1/20 0.67
GFER P55789 1/20 0.67
NLRP1 Q9C000 1/20 0.67
NOD2 Q9HC29 1/20 0.67
NPC1 O15118 3/20 0.61
RAB9A P51151 3/20 0.61
MAPK1 P28482 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL4071133 1.00 ALDH1A1 (0.93) ALDH1A1TDP1CYP3A4TSHRMAOA
Ammonia Solution, Strong SCHEMBL2578645 1.00 ALDH1A1 (0.93) ALDH1A1TDP1CYP3A4TSHRMAOA
Ammonia Solution, Strong SCHEMBL28224358 1.00 ALDH1A1 (0.93) ALDH1A1TDP1CYP3A4TSHRMAOA
SCHEMBL202864 0.97 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4TSHRMAOA
SCHEMBL2013073 0.97 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4TSHRMAOA
SCHEMBL65211 0.97 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4TSHRMAOA
SCHEMBL4446167 0.97 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4TSHRMAOA
SCHEMBL10576066 0.97 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4TSHRMAOA
SCHEMBL4455485 0.97 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4TSHRMAOA
SCHEMBL1331804 0.97 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4TSHRMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964698-B2 Wholly aromatic liquid crystalline polyetherimide (LC-PEI) resins UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2011-06-21 US claimed
US-20090118461-A1 Wholly Aromatic Liquid Crystalline Polyetherimide (LC-PEI) Resins USA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2009-05-07 US claimed