Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9123745 | 0.94 | HPRT1 (0.46) | HPRT1EDNRBEDNRANPC1RAB9A | |
| SCHEMBL15946723 | 0.94 | HPRT1 (0.46) | HPRT1EDNRBEDNRANPC1RAB9A | |
| SCHEMBL16641968 | 0.94 | HPRT1 (0.46) | HPRT1EDNRBEDNRANPC1RAB9A | |
| SCHEMBL18085708 | 0.92 | HPRT1 (0.45) | HPRT1EDNRBEDNRANPC1RAB9A | |
| SCHEMBL9407416 | 0.92 | HPRT1 (0.45) | HPRT1EDNRBEDNRANPC1RAB9A | |
| SCHEMBL17147713 | 0.92 | HPRT1 (0.45) | HPRT1EDNRBEDNRANPC1RAB9A | |
| SCHEMBL23587772 | 0.91 | MAPT (0.40) | EDNRBEDNRANPC1RAB9AMEN1 | |
| SCHEMBL18594095 | 0.91 | HPRT1 (0.41) | HPRT1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL15038402 | 0.91 | HPRT1 (0.41) | HPRT1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL21508946 | 0.91 | HPRT1 (0.41) | HPRT1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730812-B2 | Double spiro compound and organic light-emitting element comprising same | LG CHEM, LTD. (KR) | 2020-08-04 | — | — | US | disclosed |
| US-20180111887-A1 | DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730812-B2 | Double spiro compound and organic light-emitting element comprising same | NR2E3, CRY1, CRY2 | HPRT1 482/4885EDNRB 3399/4885EDNRA 2654/4885 |
| US-20180111887-A1 | DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | NR2E3, CRY1, CRY2 | HPRT1 482/4885EDNRB 3399/4885EDNRA 2654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.