SCHEMBL2009150

SCHEMBL2009150

Cc1ccc(C2Oc3ccccc3C(=O)C2(C)O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.50
DNMT3B Q9UBC3 6/20 0.46
CYP19A1 P11511 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ESR1 P03372 1/20 0.39
NR3C1 P04150 1/20 0.39
PGR P06401 1/20 0.39
NR3C2 P08235 1/20 0.39
AR P10275 1/20 0.39
ESR2 Q92731 1/20 0.39
MAPT P10636 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
ALOX12 P18054 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
SAE1 Q9UBE0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29356678 1.00 MAOB (0.50) MAOBDNMT3BCYP19A1MEN1KMT2A
SCHEMBL2009148 1.00 MAOB (0.50) MAOBDNMT3BCYP19A1MEN1KMT2A
SCHEMBL30300555 1.00 MAOB (0.50) MAOBDNMT3BCYP19A1MEN1KMT2A
SCHEMBL5313705 0.75 DNMT3B (0.57) MAOBDNMT3BCYP19A1ARMAPT
SCHEMBL2396876 0.75 MAPT (0.51) MAOBDNMT3BCYP19A1MEN1KMT2A
SCHEMBL11388124 0.74 MAOB (0.42) MAOBDNMT3BCYP19A1MEN1KMT2A
SCHEMBL11381283 0.74 MAOB (0.42) MAOBDNMT3BCYP19A1MEN1KMT2A
SCHEMBL25201529 0.73 DNMT3B (0.52) MAOBDNMT3BCYP19A1KMT2ANR3C1
SCHEMBL7120359 0.72 MAPT (0.52) MAOBDNMT3BCYP19A1MEN1KMT2A
SCHEMBL9056735 0.71 DNMT3B (0.56) MAOBDNMT3BCYP19A1ARMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106132389-B Method for producing composition containing hardly water-soluble aromatic compound 花王株式会社 2020-07-14 CN claimed
CN-106132389-A The manufacture method of the compositions containing slightly water-soluble aromatic compound 花王株式会社 2016-11-16 CN claimed
US-20100247428-A1 USES OF RARE EARTH ELEMENTS FOR HAIR IMPROVEMENT TAEWUNG ELS. INC. (KR) 2010-09-30 US claimed
EP-2066289-A1 USES OF RARE EARTH ELEMENTS FOR HAIR IMPROVEMENT Taewung Els, Inc. (KR) 2009-06-10 EP claimed
WO-2008023960-A1 USES OF RARE EARTH ELEMENTS FOR HAIR IMPROVEMENT TAEWUNG ELS, INC. (KR) 2008-02-28 WO claimed
US-12023356-B2 Stem cell filtrate preparation and method for preparing same SAEKI MASANORI (JP) 2024-07-02 US disclosed
US-11642288-B2 Skin external composition KAO CORPORATION (JP) 2023-05-09 US disclosed
CN-111491604-B Method for producing composition containing hardly water-soluble aromatic compound 花王株式会社 2023-03-21 CN disclosed
EP-4129409-A1 COMPOSITION FOR PROMOTING HAIR THICKENING, COMPOSITION FOR SUSTAINING GROWTH PHASE IN HAIR CYCLE AND COMPOSITION FOR PROMOTING VEGF PRODUCTION, COMPOSITION FOR PROMOTING TRANSITION FROM RESTING PHASE TO GROWTH PHASE IN HAIR CYCLE AND COMPOSITION FOR PROMOTING FGF7 PRODUCTION, AND COMPOSITION FOR PROMOTING HAIR CYCLE NORMALIZATION AJINOMOTO CO., INC. (JP) 2023-02-08 EP disclosed
US-20230023463-A1 COMPOSITION FOR PROMOTING HAIR THICKENING, COMPOSITION FOR SUSTAINING GROWTH PHASE IN HAIR CYCLE AND COMPOSITION FOR PROMOTING VEGF PRODUCTION, COMPOSITION FOR PROMOTING TRANSITION FROM RESTING PHASE TO GROWTH PHASE IN HAIR CYCLE AND COMPOSITION FOR PROMOTING FGF7 PRODUCTION, AND COMPOSITION FOR PROMOTING HAIR CYCLE NORMALIZATION AJINOMOTO CO., INC. (JP) 2023-01-26 US disclosed
EP-4104862-A1 SKIN COMPOSITION FOR EXTERNAL USE Kao Corporation (JP) 2022-12-21 EP disclosed
EP-3733155-B1 METHOD FOR MANUFACTURING COMPOSITION THAT INCLUDES POORLY WATER-SOLUBLE AROMATIC COMPOUND KAO CORP (JP) 2022-11-23 EP disclosed
EP-1962090-A1 Method for evaluating or screening hair growth-regulating agent Kao Corporation (JP) 2008-08-27 EP disclosed
US-20080181976-A1 AQUEOUS EXTERNAL PREPARATION FOR SCALP KAO CORPORATION (JP) 2008-07-31 US disclosed
WO-2008023960-A1 USES OF RARE EARTH ELEMENTS FOR HAIR IMPROVEMENT TAEWUNG ELS, INC. (KR) 2008-02-28 WO disclosed
JP-2007204426-A HAIR GROWTH PROMOTER KANEBO COSMETICS INC 2007-08-16 JP disclosed
EP-1683512-A1 Hair conditioning composition containing flavone derivatives KPSS-Kao Professional Salon Services GmbH (DE) 2006-07-26 EP disclosed
US-20060140887-A1 Hair conditioning composition KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2006-06-29 US disclosed
JP-2006143640-A HAIR TONIC OR GROWING AGENT KAO CORP 2006-06-08 JP disclosed
JP-2000198779-A PURIFICATION OF 3-ALKYLFLAVANOL DERIVATIVE KAO CORP 2000-07-18 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060140887-A1 Hair conditioning composition HAAO, HAO1, HAO2 MAOB 622/4885DNMT3B 244/4885CYP19A1 579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.