SCHEMBL200916

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL200917	1.00	PPARA (0.44)	PPARACYSLTR2CYSLTR1KDM4ESOAT1
	SCHEMBL202544	0.84	PARP10 (0.41)	—
	SCHEMBL202545	0.84	PARP10 (0.41)	—
	SCHEMBL201493	0.83	MEN1 (0.54)	MEN1CYP3A4KMT2ATP53NR1I2
	SCHEMBL204373	0.83	MEN1 (0.54)	MEN1CYP3A4KMT2ATP53NR1I2
	SCHEMBL201612	0.83	MEN1 (0.54)	MEN1CYP3A4KMT2ATP53NR1I2
	SCHEMBL201514	0.78	FAAH (0.59)	PPARACYSLTR2CYSLTR1KDM4EFAAH
	SCHEMBL201463	0.78	FAAH (0.59)	PPARACYSLTR2CYSLTR1KDM4EFAAH
	SCHEMBL201462	0.78	FAAH (0.59)	PPARACYSLTR2CYSLTR1KDM4EFAAH
	SCHEMBL203639	0.76	KDM4E (0.42)	PPARACYSLTR2CYSLTR1KDM4ESOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.