Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 9/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13718825 | 0.83 | PIK3CD (0.42) | CYP3A4CYP2D6CYP2C9PIK3CDPIK3CG | |
| SCHEMBL13828449 | 0.77 | PIK3CD (0.40) | PIK3CDPIK3CGPIK3R1CSNK1EAR | |
| SCHEMBL13717707 | 0.77 | PIK3CD (0.40) | PIK3CDPIK3CGPIK3R1CSNK1EAR | |
| SCHEMBL30522469 | 0.77 | PIK3CD (0.40) | PIK3CDPIK3CGPIK3R1CSNK1EAR | |
| SCHEMBL13826607 | 0.77 | PIK3CD (0.40) | PIK3CDPIK3CGPIK3R1CSNK1EAR | |
| SCHEMBL13826019 | 0.77 | PIK3CD (0.40) | PIK3CDPIK3CGPIK3R1CSNK1EAR | |
| SCHEMBL13825936 | 0.77 | AR (0.42) | PIK3CDPIK3CGPIK3R1CSNK1EAR | |
| SCHEMBL13828422 | 0.75 | PIK3CD (0.40) | PIK3CDPIK3CGPIK3R1CSNK1EAR | |
| SCHEMBL29895849 | 0.75 | PIK3CD (0.40) | PIK3CDPIK3CGPIK3R1CSNK1EAR | |
| SCHEMBL13826012 | 0.75 | AR (0.40) | PIK3CDPIK3CGPIK3R1CSNK1EAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190105324-A9 | SUBSTITUTED CHROMENONES AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS AG (CH) | 2019-04-11 | — | — | US | disclosed |
| US-20180110783-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS SA (CH) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190105324-A9 | SUBSTITUTED CHROMENONES AS MODULATORS OF PROTEIN KINASES | PRKCA, PRKCH, PRKAR2B | CYP3A4 3614/4885CYP2D6 4166/4885CYP2C9 4514/4885 |
| US-20180110783-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | PRKCA, PRKCH, PRKCB | CYP3A4 4586/4885CYP2D6 4626/4885CYP2C9 4828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.