⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889404 | 0.90 | — | — | |
| SCHEMBL4857665 | 0.83 | — | — | |
| SCHEMBL22147424 | 0.81 | — | — | |
| SCHEMBL22147420 | 0.81 | — | — | |
| SCHEMBL160486 | 0.78 | TSHR (0.36) | — | |
| SCHEMBL997337 | 0.78 | TSHR (0.36) | — | |
| SCHEMBL2208055 | 0.78 | TSHR (0.36) | — | |
| SCHEMBL714832 | 0.75 | TDP1 (0.38) | — | |
| SCHEMBL12432165 | 0.75 | — | — | |
| SCHEMBL1804131 | 0.74 | TDP1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190233556-A1 | HIGH REFRACTIVE INDEX POLYMERIZABLE MONOMERS AND APPLICATIONS THEREOF | CORNING INCORPORATED (US) | 2019-08-01 | — | — | US | disclosed |
| WO-2018075848-A1 | HIGH REFRACTIVE INDEX POLYMERIZABLE MONOMERS AND APPLICATIONS THEREOF | CORNING INCORPORATED (US) | 2018-04-26 | — | — | WO | disclosed |