Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL3139524 | 0.92 | TDP1 (0.33) | TDP1CYP2C19 | |
| SCHEMBL997337 | 0.92 | TSHR (0.36) | TDP1CYP2C19TSHR | |
| SCHEMBL9546898 | 0.92 | TDP1 (0.33) | TDP1CYP2C19TSHR | |
| SCHEMBL2208055 | 0.92 | TSHR (0.36) | TDP1CYP2C19TSHR | |
| SCHEMBL160486 | 0.92 | TSHR (0.36) | TDP1CYP2C19TSHR | |
| SCHEMBL7180847 | 0.90 | ALDH1A1 (0.38) | TDP1ALDH1A1 | |
| SCHEMBL1802969 | 0.89 | TDP1 (0.35) | TDP1ALDH1A1CYP2C19POLBBLM | |
| SCHEMBL1802245 | 0.89 | TDP1 (0.35) | TDP1ALDH1A1CYP2C19POLBBLM | |
| SCHEMBL1804131 | 0.88 | TDP1 (0.31) | TDP1 | |
| SCHEMBL9794648 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022496-A | Chromene compound | TOKUYAMA CORPORATION (JP) | 2000-02-08 | — | — | US | claimed |
| EP-0745620-A1 | Polymerisable compositions based on thio(meth)acrylate monomers, polymers having low yellowness index made from these compositions and ophthalmic lenses made therefrom | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1996-12-04 | — | — | EP | claimed |
| US-12624048-B2 | Photochromic cyclic compound and curable composition containing the photochromic cyclic compound | TOKUYAMA CORPORATION (JP) | 2026-05-12 | — | — | US | disclosed |
| US-12595408-B2 | Photochromic compound, naphthol derivative, curable composition, optical article, lens, and eyeglasses | TOKUYAMA CORPORATION (JP) | 2026-04-07 | — | — | US | disclosed |
| US-12570894-B2 | Photochromic compound and curable composition containing the photochromic compound | TOKUYAMA CORPORATION (JP) | 2026-03-10 | — | — | US | disclosed |
| EP-4692071-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS | TOKUYAMA CORPORATION (JP) | 2026-02-11 | — | — | EP | disclosed |
| EP-4692072-A1 | PHOTOCHROMIC COMPOUND, PROPARGYL ALCOHOL COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND SPECTACLES | TOKUYAMA CORPORATION (JP) | 2026-02-11 | — | — | EP | disclosed |
| EP-3779572-B1 | OPTICAL ARTICLE | HOYA LENS THAILAND LTD (TH) | 2025-11-19 | — | — | EP | disclosed |
| US-20250122163-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | TOKUYAMA CORPORATION (JP) | 2025-04-17 | — | — | US | disclosed |
| WO-2025070122-A1 | PHOTOCHROMIC COMPOSITION, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2025-04-03 | — | — | WO | disclosed |
| US-20250101294-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | TOKUYAMA CORPORATION (JP) | 2025-03-27 | — | — | US | disclosed |
| EP-0745620-A1 | Polymerisable compositions based on thio(meth)acrylate monomers, polymers having low yellowness index made from these compositions and ophthalmic lenses made therefrom | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1996-12-04 | — | — | EP | disclosed |
| EP-0273710-B2 | Resin having high refractive index, process for producing said resin and optical materials composed of said resin | NIPPON CATALYTIC CHEM IND (JP) | 1996-10-16 | — | — | EP | disclosed |
| EP-0696582-A1 | Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides | TOKUYAMA CORPORATION (JP) | 1996-02-14 | — | — | EP | disclosed |
| US-5389708-A | Polymerizing polyisocyanate or polyisothiocyanate with polyol or polythiol in presence of thiophosphoric or dithiophosphoric acid ester | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0629626-A2 | Cyclopropyl-substituted spiro-photochromic compounds | TOKUYAMA CORPORATION (JP) | 1994-12-21 | — | — | EP | disclosed |
| EP-0629656-A2 | Photochromic article | NIKON CORPORATION (JP) | 1994-12-21 | — | — | EP | disclosed |
| EP-0553801-A1 | Use of sulfur-containing acid phosphoric ester as internal release agent | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-4931521-A | Optical materials composed of resin from thioacrylat esters | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1990-06-05 | — | — | US | disclosed |
| EP-0273710-A2 | Resin having high refractive index, process for producing said resin and optical materials composed of said resin | Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) | 1988-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595408-B2 | Photochromic compound, naphthol derivative, curable composition, optical article, lens, and eyeglasses | CRYAA, CRYZ, CRY2 | TDP1 4080/4885ALDH1A1 185/4885CYP2C19 2136/4885 |
| US-20250122163-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | CCNE1, NAP1L1, CRYZ | TDP1 2884/4885ALDH1A1 1010/4885CYP2C19 2138/4885 |
| US-12570894-B2 | Photochromic compound and curable composition containing the photochromic compound | SMC4, HBG2, SPTBN1 | TDP1 4632/4885ALDH1A1 2699/4885CYP2C19 4223/4885 |
| US-20250101294-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | NAP1L1, CRYAA, CRYZ | TDP1 3867/4885ALDH1A1 224/4885CYP2C19 1933/4885 |
| US-12624048-B2 | Photochromic cyclic compound and curable composition containing the photochromic cyclic compound | CCNL2, CRY2, CRY1 | TDP1 4237/4885ALDH1A1 1492/4885CYP2C19 2179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.