SCHEMBL997337

SCHEMBL997337

C=C(C)C(=O)SCCSCCSCCSCCSC(=O)C(=C)C

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 2/20 0.33
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2208055 1.00 TSHR (0.36) TSHRTDP1LMNAKMT2AHSD17B10
SCHEMBL160486 1.00 TSHR (0.36) TSHRTDP1LMNAKMT2AHSD17B10
SCHEMBL8985546 0.93 CES2 (0.32) TSHR
SCHEMBL714832 0.92 TDP1 (0.38) TSHRTDP1CYP2C19
SCHEMBL18139097 0.91 TDP1 (0.42) TSHRTDP1
SCHEMBL8985594 0.91 CES2 (0.31) TSHR
SCHEMBL18139594 0.91 TDP1 (0.42) TSHRTDP1
SCHEMBL1804131 0.91 TDP1 (0.31) TDP1
SCHEMBL6312536 0.89 TSHR (0.30) TSHR
SCHEMBL14254732 0.89 TSHR (0.39) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10040947-B2 Primer composition MITSUI CHEMICALS, INC. (JP) 2018-08-07 US disclosed
US-20180163056-A1 HYDROPHILIC CURABLE COMPOSITIONS MITSUI CHEMICALS, INC. (JP) 2018-06-14 US disclosed
US-20180036995-A1 HYDROPHILIC MONOLAYER FILM WITH OPTICAL FUNCTIONALITY AND STACK OF THE SAME MITSUI CHEMICALS, INC. (JP) 2018-02-08 US disclosed
EP-3270192-A1 HYDROPHILIC SINGLE-LAYER FILM HAVING OPTICAL FUNCTIONALITY, AND LAMINATE THEREOF Mitsui Chemicals, Inc. (JP) 2018-01-17 EP disclosed
US-20170209345-A1 DENTAL PROSTHESIS MITSUI CHEMICALS, INC. (JP) 2017-07-27 US disclosed
EP-3081578-A1 COMPOSITION FOR HYDROPHILIC CURED PRODUCT Mitsui Chemicals, Inc. (JP) 2016-10-19 EP disclosed
EP-2599799-B1 SINGLE-LAYER FILM AND HYDROPHILIC MATERIAL COMPRISING SAME MITSUI CHEMICALS INC (JP) 2016-05-25 EP disclosed
US-9238769-B2 Monolayer film and hydrophilic material comprising the same MITSUI CHEMICALS, INC. (JP) 2016-01-19 US disclosed
US-9034464-B2 Single layer film and hydrophilic material comprising the same MITSUI CHEMICALS, INC. (JP) 2015-05-19 US disclosed
US-20140154451-A1 MONOLAYER FILM AND HYDROPHILIC MATERIAL COMPRISING THE SAME MITSUI CHEMICALS, INC. 2014-06-05 US disclosed
EP-1291388-B1 CURABLE COMPOSITION AND PHOTOCHROMIC CURED ARTICLE TOKUYAMA CORP (JP) 2005-07-13 EP disclosed
WO-2004092787-A1 PHOTOCURABLE ADHESIVE COMPOSITION AND ITS USE IN THE OPTICAL FIELD ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2004-10-28 WO disclosed
US-6698883-B2 COLOR DENSITY AND A LARGE FADING RATE, HARDNESS, HEAT RESISTANCE AND SHOCK RESISTANCE; AS OPTICAL MATERIAL SUCH AS A PHOTOCHROMIC LENS MATERIAL TOKUYAMA CORPORATION (JP) 2004-03-02 US disclosed
US-6635730-B1 Photopolymerizable composition forming lenses with low yellowing index and good resistance to aging ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2003-10-21 US disclosed
US-6627718-B2 Polythio(meth)acrylate, bridged ethylenically unsaturated monomoer, and polythiol ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2003-09-30 US disclosed
US-20030109655-A1 Polymerizable compositions for making optical lens with high refractive index and high abbe number, and resulting lens ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2003-06-12 US disclosed
EP-1291388-A1 CURABLE COMPOSITION AND PHOTOCHROMIC CURED ARTICLE TOKUYAMA CORPORATION (JP) 2003-03-12 EP disclosed
US-20030008958-A1 Curable composition and photochromic cured article TOKUYAMA CORPORATION (JP) 2003-01-09 US disclosed
EP-1130038-A1 CURABLE COMPOSITION TOKUYAMA CORPORATION (JP) 2001-09-05 EP disclosed
EP-0273710-B2 Resin having high refractive index, process for producing said resin and optical materials composed of said resin NIPPON CATALYTIC CHEM IND (JP) 1996-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170209345-A1 DENTAL PROSTHESIS CAD, OR10J3, PSMA3 TSHR 3424/4885TDP1 3535/4885LMNA 4235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.