SCHEMBL2009505

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2009318	0.88	MAPT (0.42)	MAPK14PIP4K2AMAPTTP53POLB
	SCHEMBL2011809	0.83	ALDH1A1 (0.48)	MAPK14RXFP1MAPTTP53POLB
	SCHEMBL2006258	0.82	NR3C1 (0.41)	MAPK14MAPTPOLBMRGPRX4PTGER1
	SCHEMBL25678123	0.81	ALDH1A1 (0.47)	MAPK14MAPTTP53POLBALDH1A1
	SCHEMBL25232839	0.76	CCR1 (0.48)	MAPK14
	SCHEMBL30481251	0.76	CCR1 (0.48)	MAPK14
	SCHEMBL2007484	0.76	MAPK14 (0.41)	MAPK14MAPTPOLBMRGPRX4SMN1; SMN2
	SCHEMBL14085312	0.75	CYP11B1 (0.42)	MAPK14RXFP1MAPTTP53MRGPRX4
	SCHEMBL2007006	0.75	PIP4K2A (0.41)	MAPK14PIP4K2ARXFP1MAPTMRGPRX4
	SCHEMBL29509768	0.75	NR3C1 (0.46)	MAPK14RHEB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.