Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27783713 | 1.00 | MAPKAPK2 (0.54) | MAPKAPK2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL430689 | 1.00 | MAPKAPK2 (0.54) | MAPKAPK2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29741303 | 0.87 | TEAD4 (0.47) | MAPKAPK2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29741345 | 0.87 | MAPT (0.52) | MAPKAPK2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL27805310 | 0.87 | KMT2A (0.49) | MAPKAPK2JAK3IRAK4MAPTEGFR | |
| SCHEMBL29741354 | 0.87 | TEAD4 (0.47) | MAPKAPK2JAK3IRAK4LMNAKDM4E | |
| SCHEMBL431571 | 0.87 | NPBWR1 (0.54) | MAPKAPK2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28786965 | 0.87 | KMT2A (0.49) | MAPKAPK2JAK3IRAK4MAPTEGFR | |
| SCHEMBL27805313 | 0.87 | KMT2A (0.49) | MAPKAPK2JAK3IRAK4MAPTEGFR | |
| SCHEMBL5501697 | 0.83 | PRKACA (0.47) | MAPKAPK2CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114836486-B | Method for synthesizing chiral beta-amino alcohol by enzyme catalysis | 湖北大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-114836486-A | Method for synthesizing chiral beta-amino alcohol by enzyme catalysis | 湖北大学 | 2022-08-02 | — | — | CN | disclosed |
| US-10882870-B2 | Crystalline metal organic framework | FUNDACIÓ INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) | 2021-01-05 | — | — | US | disclosed |
| EP-3529252-B1 | A CRYSTALLINE METAL ORGANIC FRAMEWORK | FUNDACIO INSTITUT CATALA DINVESTIGACIO QUIM ICIQ (ES) | 2020-12-09 | — | — | EP | disclosed |
| US-20190256528-A1 | A CRYSTALLINE METAL ORGANIC FRAMEWORK | INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS (ES) | 2019-08-22 | — | — | US | disclosed |
| WO-2018073400-A1 | A CRYSTALLINE METAL ORGANIC FRAMEWORK | FUNDACIÓ INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) | 2018-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256528-A1 | A CRYSTALLINE METAL ORGANIC FRAMEWORK | HNRNPF, POF1B, RTRAF | MAPKAPK2 4259/4885CYP1A2 1565/4885CYP3A4 1496/4885 |
| US-10882870-B2 | Crystalline metal organic framework | POF1B, HNRNPF, RTRAF | MAPKAPK2 4208/4885CYP1A2 1666/4885CYP3A4 1660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.