Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27783713 | 1.00 | MAPKAPK2 (0.54) | MAPKAPK2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20095129 | 1.00 | MAPKAPK2 (0.54) | MAPKAPK2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29741303 | 0.87 | TEAD4 (0.47) | MAPKAPK2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29741345 | 0.87 | MAPT (0.52) | MAPKAPK2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL27805310 | 0.87 | KMT2A (0.49) | MAPKAPK2JAK3IRAK4MAPTEGFR | |
| SCHEMBL29741354 | 0.87 | TEAD4 (0.47) | MAPKAPK2JAK3IRAK4LMNAKDM4E | |
| SCHEMBL431571 | 0.87 | NPBWR1 (0.54) | MAPKAPK2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28786965 | 0.87 | KMT2A (0.49) | MAPKAPK2JAK3IRAK4MAPTEGFR | |
| SCHEMBL27805313 | 0.87 | KMT2A (0.49) | MAPKAPK2JAK3IRAK4MAPTEGFR | |
| SCHEMBL5501697 | 0.83 | PRKACA (0.47) | MAPKAPK2CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114836486-B | Method for synthesizing chiral beta-amino alcohol by enzyme catalysis | 湖北大学 | 2023-05-12 | — | — | CN | claimed |
| CN-114836486-A | Method for synthesizing chiral beta-amino alcohol by enzyme catalysis | 湖北大学 | 2022-08-02 | — | — | CN | claimed |
| CN-114836486-B | Method for synthesizing chiral beta-amino alcohol by enzyme catalysis | 湖北大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-114836486-A | Method for synthesizing chiral beta-amino alcohol by enzyme catalysis | 湖北大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-110167948-B | Crystalline metal organic framework | 卡塔拉基础学院化学研究所 | 2022-01-11 | — | — | CN | disclosed |
| CN-104529796-A | Catalytic synthesis application based on frustrated Lewis acid-base pair | UNIV HUNAN | 2015-04-22 | — | — | CN | disclosed |
| US-8932980-B2 | Ordered mesoporous titanosilicate and the process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-01-13 | — | — | US | disclosed |
| EP-2595921-A1 | ORDERED MESOPOROUS TITANOSILICATE AND THE PROCESS FOR THE PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2013-05-29 | — | — | EP | disclosed |
| US-20130116453-A1 | ORDERED MESOPOROUS TITANOSILICATE AND THE PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-05-09 | — | — | US | disclosed |
| WO-2012011124-A1 | ORDERED MESOPOROUS TITANOSILICATE AND THE PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-01-26 | — | — | WO | disclosed |
| CN-101747211-A | Synthesis method of derivative of chiral Beta-amino-alcohol and part of final products thereof | ASYMCHEM LIFE SCIENCE TIANJIN | 2010-06-23 | — | — | CN | disclosed |
| EP-0137251-B1 | BISMORPHOLINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTI-HYDROLYSIS AGENTS | BAYER AG (DE) | 1988-09-28 | — | — | EP | disclosed |
| US-4639478-A | Bismorpholines, a process for their preparation and their use for protection against hydrolysis | BAYER AKTIENGESELLSCHAFT (DE) | 1987-01-27 | — | — | US | disclosed |
| US-4617387-A | REACTING GLYOXAL WITH AN N-SUBSTITUTED AMINO ALCOHOL | BAYER AKTIENGESELLSCHAFT (DE) | 1986-10-14 | — | — | US | disclosed |
| EP-0137251-A2 | Bismorpholines, process for their preparation and their use as anti-hydrolysis agents | BAYER AG (DE) | 1985-04-17 | — | — | EP | disclosed |