Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | IGF2R | P11717 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22452303 | 0.86 | TLR4 (0.45) | TLR4PTPN1L3MBTL1MEN1KMT2A | |
| SCHEMBL19958457 | 0.80 | TLR4 (0.50) | TLR4PTPN1IGF2RCA2MEN1 | |
| SCHEMBL17853226 | 0.80 | TLR4 (0.49) | TLR4PTPN1L3MBTL1MEN1KMT2A | |
| SCHEMBL19961526 | 0.80 | TLR4 (0.49) | TLR4PTPN1L3MBTL1MEN1KMT2A | |
| SCHEMBL19901290 | 0.80 | L3MBTL1 (0.48) | TLR4PTPN1L3MBTL1MEN1KMT2A | |
| SCHEMBL19958445 | 0.80 | TLR4 (0.49) | TLR4PTPN1L3MBTL1MEN1KMT2A | |
| SCHEMBL16361991 | 0.80 | TLR4 (0.49) | TLR4PTPN1L3MBTL1MEN1KMT2A | |
| SCHEMBL21944328 | 0.80 | TLR4 (0.49) | TLR4PTPN1L3MBTL1MEN1KMT2A | |
| SCHEMBL21943693 | 0.80 | TLR4 (0.49) | TLR4PTPN1L3MBTL1MEN1KMT2A | |
| SCHEMBL16351450 | 0.80 | TLR4 (0.49) | TLR4PTPN1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10273333-B2 | Substituted polyesters by thiol-ene modification: rapid diversification for therapeutic protein stabilization | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-04-30 | — | — | US | disclosed |
| US-20180112034-A1 | SUBSTITUTED POLYESTERS BY THIOL-ENE MODIFICATION: RAPID DIVERSIFICATION FOR THERAPEUTIC PROTEIN STABILIZATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180112034-A1 | SUBSTITUTED POLYESTERS BY THIOL-ENE MODIFICATION: RAPID DIVERSIFICATION FOR THERAPEUTIC PROTEIN STABILIZATION | TREH, MGAM, TRRAP | TLR4 1263/4885PTPN1 2093/4885IGF2R 25/4885 |
| US-10273333-B2 | Substituted polyesters by thiol-ene modification: rapid diversification for therapeutic protein stabilization | TREH, MGAM, TRRAP | TLR4 1263/4885PTPN1 2093/4885IGF2R 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.