Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20095343 | 0.87 | PTGS1 (0.58) | PTGS1ALOX5LMNAKMT2AMAPT | |
| SCHEMBL810128 | 0.80 | PTGS1 (0.51) | PTGS1ALOX5LMNAKMT2AMAPT | |
| SCHEMBL24201975 | 0.79 | PTGS1 (0.48) | PTGS1MAPTKDM4EALDH1A1GAA | |
| SCHEMBL20089609 | 0.78 | PTGS1 (0.44) | PTGS1ALOX5KDM4EALDH1A1GAA | |
| SCHEMBL9749313 | 0.77 | LIG1 (0.54) | PTGS1LMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL11891610 | 0.76 | PTGS1 (0.85) | PTGS1ALOX5LMNAKMT2AMAPT | |
| SCHEMBL11716714 | 0.75 | AKR1C3 (0.57) | ALOX5LMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL11716703 | 0.75 | AKR1C3 (0.57) | ALOX5LMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL6691655 | 0.74 | GAA (0.61) | PTGS1ALOX5LMNAKMT2AMAPT | |
| SCHEMBL6686762 | 0.74 | KDM4E (0.47) | PTGS1ALOX5LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315126-B1 | CONJUGATE OF POLYETHYLENE GLYCOL AND ANESTHETIC, AND PREPARATION METHOD THEREOF | JENKEM TECH CO LTD TIANJIN (CN) | 2022-01-19 | — | — | EP | disclosed |
| EP-3563873-A1 | APPLICATION OF COMBINATION OF POLYETHYLENE GLYCOL AND LOCAL ANESTHETIC IN NON-NARCOTIC ANALGESIA | Jenkem Technology Co., Ltd. (Tianjin) (CN) | 2019-11-06 | — | — | EP | disclosed |
| US-20180110867-A1 | CONJUGATE OF POLYETHYLENE GLYCOL AND ANESTHETIC, AND PREPARATION METHOD THEREOF | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180110867-A1 | CONJUGATE OF POLYETHYLENE GLYCOL AND ANESTHETIC, AND PREPARATION METHOD THEREOF | OPRL1, OGFR, F12 | PTGS1 248/4885ALOX5 1640/4885LMNA 3588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.