Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20095777 | 0.82 | ADH1A (0.33) | — | |
| SCHEMBL20095774 | 0.81 | SLC18A3 (0.32) | — | |
| SCHEMBL20096038 | 0.81 | — | — | |
| SCHEMBL20096127 | 0.78 | — | — | |
| SCHEMBL20095776 | 0.76 | ADRA1B (0.32) | — | |
| SCHEMBL20096037 | 0.76 | ADRA1B (0.32) | — | |
| SCHEMBL20096120 | 0.74 | — | — | |
| SCHEMBL20143452 | 0.74 | — | — | |
| SCHEMBL20096291 | 0.72 | — | — | |
| SCHEMBL20095912 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018072602-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2018-04-26 | — | — | WO | disclosed |