Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 2/20 | 0.32 |
| ▸ | ILK | Q13418 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA7 | P43166 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
| ▸ | DPP4 | P27487 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25842444 | 0.89 | CA1 (0.38) | SOS1CFTRALDH1A1KDM4EKMT2A | |
| SCHEMBL17381631 | 0.80 | MAPT (0.41) | ALDH1A1KDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL15601633 | 0.79 | TDP1 (0.34) | CFTRALDH1A1KDM4ESLC6A3POLB | |
| SCHEMBL24298962 | 0.75 | SLC6A3 (0.45) | CFTRALDH1A1KDM4EKMT2ASLC6A3 | |
| SCHEMBL522786 | 0.74 | CA12 (0.47) | SOS1CFTRALDH1A1KDM4ESLC6A3 | |
| SCHEMBL24525250 | 0.73 | — | — | |
| SCHEMBL410165 | 0.71 | ALPL (0.45) | PKMSOS1CFTRALDH1A1KDM4E | |
| SCHEMBL16846491 | 0.69 | TDP1 (0.44) | ALDH1A1KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL27396798 | 0.69 | KDM4E (0.42) | CFTRALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL17114126 | 0.69 | CA12 (0.42) | ALDH1A1KDM4EKMT2APOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075871-A1 | NOVEL ANTIBIOTICS AND METHODS OF USING SAME | THE BROAD INSTITUTE, INC. (US) | 2018-04-26 | — | — | WO | disclosed |