Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.69 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RORA | P35398 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | RORB | Q92753 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12354899 | 0.92 | KIF11 (0.57) | KIF11BCHEACHETP53MAPT | |
| SCHEMBL21454581 | 0.86 | KIF11 (0.82) | KIF11MAPTKDM4EPKMRORC | |
| SCHEMBL13564051 | 0.86 | KIF11 (0.51) | KIF11BCHEACHETP53MAPT | |
| SCHEMBL13564053 | 0.84 | KIF11 (0.59) | KIF11TP53MAPTKDM4EAPAF1 | |
| SCHEMBL20466817 | 0.82 | BCHE (0.54) | KIF11BCHEACHEMAPTKDM4E | |
| SCHEMBL13383054 | 0.82 | KIF11 (0.65) | KIF11MAPTKDM4EPKMHTT | |
| SCHEMBL21454578 | 0.81 | KIF11 (1.00) | KIF11MAPTKDM4EHTTRAB9A | |
| SCHEMBL21311348 | 0.80 | ALDH1A1 (0.46) | KIF11TP53RORARORCRORB | |
| SCHEMBL25490702 | 0.80 | KIF11 (0.46) | KIF11BCHEACHEMAPTKDM4E | |
| SCHEMBL20096916 | 0.80 | KIF11 (0.49) | KIF11BCHEACHEMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |