Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | PER2 | O15055 | 5/20 | 0.36 |
| ▸ | CRY1 | Q16526 | 5/20 | 0.36 |
| ▸ | CRY2 | Q49AN0 | 5/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20096974 | 0.88 | NR1I2 (0.47) | NPY5RMEN1KMT2ANR1I2EGFR | |
| SCHEMBL13338392 | 0.84 | MEN1 (0.45) | NPY5RMEN1KMT2ANR1I2EGFR | |
| SCHEMBL20097051 | 0.81 | ATM (0.50) | NPY5RMEN1KMT2AKIF11CYP11B1 | |
| SCHEMBL19373828 | 0.80 | NR1I2 (0.51) | NPY5RMEN1KMT2ANR1I2EGFR | |
| SCHEMBL21311348 | 0.80 | ALDH1A1 (0.46) | NPY5RMEN1KMT2ANR1I2EGFR | |
| SCHEMBL26996620 | 0.80 | MEN1 (0.40) | NPY5RMEN1KMT2ANR1I2EGFR | |
| SCHEMBL15458634 | 0.80 | MEN1 (0.58) | NPY5RMEN1KMT2ANR1I2EGFR | |
| SCHEMBL27586281 | 0.78 | MEN1 (0.56) | NPY5RMEN1KMT2APER2ATM | |
| SCHEMBL12050152 | 0.76 | NR1I2 (0.52) | NPY5RMEN1KMT2ANR1I2EGFR | |
| SCHEMBL22336506 | 0.76 | NR1I2 (0.46) | NPY5RMEN1KMT2ANR1I2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-08-29 | — | — | US | disclosed |
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | POLRMT, EIF2AK2, NSUN3 | NPY5R 4867/4885MEN1 4786/4885KMT2A 2961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.