Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | GMPS | P49915 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AHCY | P23526 | 5/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21311235 | 0.79 | DOT1L (0.56) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL3794703 | 0.75 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL18537398 | 0.75 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL29375670 | 0.75 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL41360 | 0.75 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL13061814 | 0.75 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL16258664 | 0.75 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL18680910 | 0.75 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL20143496 | 0.75 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL13010067 | 0.75 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |