Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 6/20 | 0.34 |
| ▸ | JAK3 | P52333 | 6/20 | 0.34 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16197154 | 0.79 | SIRT3 (0.36) | FGFR1LTA4HSMN1; SMN2DYRK1AASAH1 | |
| SCHEMBL29585279 | 0.77 | SMN1; SMN2 (0.54) | FGFR1DNMT3ASMN1; SMN2LMNASTAT6 | |
| SCHEMBL28377896 | 0.77 | SMN1; SMN2 (0.54) | FGFR1DNMT3ASMN1; SMN2LMNASTAT6 | |
| SCHEMBL12414508 | 0.76 | SMN1; SMN2 (0.48) | JAK2JAK3SMN1; SMN2 | |
| SCHEMBL27582500 | 0.76 | LTA4H (0.35) | FGFR1LTA4HJAK2JAK3DNMT3A | |
| SCHEMBL4886319 | 0.73 | MKNK1 (0.40) | LTA4HASAH1CYP2C9IDO1KCNH2 | |
| SCHEMBL84793 | 0.72 | LTA4H (0.41) | FGFR1LTA4HJAK2JAK3NFATC1 | |
| SCHEMBL7020729 | 0.72 | FGFR1 (0.41) | FGFR1LTA4HJAK2JAK3SMN1; SMN2 | |
| SCHEMBL13083686 | 0.70 | FGFR1 (0.42) | FGFR1LTA4HJAK2JAK3SMN1; SMN2 | |
| SCHEMBL1106468 | 0.68 | NFATC1 (0.45) | FGFR1LTA4HJAK2JAK3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |