Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 9/20 | 0.35 |
| ▸ | JAK3 | P52333 | 9/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25291568 | 0.83 | FGFR1 (0.53) | FGFR1LTA4HJAK2JAK3SMN1; SMN2 | |
| SCHEMBL13083686 | 0.77 | FGFR1 (0.42) | FGFR1LTA4HJAK2JAK3SMN1; SMN2 | |
| SCHEMBL84793 | 0.75 | LTA4H (0.41) | FGFR1LTA4HJAK2JAK3MAPT | |
| SCHEMBL10280661 | 0.75 | MAPK13 (0.39) | FGFR1LTA4HJAK2JAK3SMN1; SMN2 | |
| SCHEMBL20097035 | 0.72 | FGFR1 (0.36) | FGFR1LTA4HJAK2JAK3SMN1; SMN2 | |
| SCHEMBL293614 | 0.71 | TDP1 (0.54) | FGFR1SMN1; SMN2POLB | |
| SCHEMBL7105950 | 0.71 | LTA4H (0.51) | LTA4HSMN1; SMN2MAPT | |
| SCHEMBL1106468 | 0.71 | NFATC1 (0.45) | FGFR1LTA4HJAK2JAK3SMN1; SMN2 | |
| SCHEMBL7975287 | 0.71 | LTA4H (0.48) | FGFR1LTA4HSMN1; SMN2MAPT | |
| SCHEMBL11900775 | 0.69 | FGFR1 (0.75) | FGFR1JAK2JAK3CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946202-B1 | CONTRAST AGENTS | AMERSHAM HEALTH AS (NO) | 2003-09-10 | — | — | EP | disclosed |
| US-6051207-A | PHOSPHATIDYLSERINE LINKED ISOXAZOLE SULFONAMIDE DERIVATIVES; DIAGNOSING AND IMAGING CARDIOVASCULAR DISORDERS | NYCOMED IMAGING AS (NO) | 2000-04-18 | — | — | US | disclosed |