Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 1/20 | 1.00 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.79 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 0.79 |
| ▸ | WDR5 | P61964 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | RBBP5 | Q15291 | 1/20 | 0.78 |
| ▸ | DPY30 | Q9C005 | 1/20 | 0.78 |
| ▸ | ASH2L | Q9UBL3 | 1/20 | 0.78 |
| ▸ | DOT1L | Q8TEK3 | 5/20 | 0.77 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.75 |
| ▸ | TRDMT1 | O14717 | 6/20 | 0.75 |
| ▸ | NNMT | P40261 | 2/20 | 0.72 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.72 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.72 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.72 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.71 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.71 |
| ▸ | RNMT | O43148 | 1/20 | 0.71 |
| ▸ | INMT | O95050 | 1/20 | 0.71 |
| ▸ | NSD2 | O96028 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL505843 | 1.00 | EZH2 (1.00) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL4319361 | 1.00 | EZH2 (1.00) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL14174648 | 1.00 | EZH2 (1.00) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL4319379 | 1.00 | EZH2 (1.00) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL19111331 | 0.95 | EZH2 (0.90) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL23120178 | 0.91 | WDR5 (0.93) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL25434994 | 0.90 | EZH2 (0.81) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL19111319 | 0.90 | EZH2 (0.81) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL23120131 | 0.89 | SMYD3 (0.87) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL13986292 | 0.89 | SMYD3 (1.00) | EZH2SMYD3SETD2WDR5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |