Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 1/20 | 1.00 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.79 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 0.79 |
| ▸ | WDR5 | P61964 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | RBBP5 | Q15291 | 1/20 | 0.78 |
| ▸ | DPY30 | Q9C005 | 1/20 | 0.78 |
| ▸ | ASH2L | Q9UBL3 | 1/20 | 0.78 |
| ▸ | DOT1L | Q8TEK3 | 5/20 | 0.77 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.75 |
| ▸ | TRDMT1 | O14717 | 6/20 | 0.75 |
| ▸ | NNMT | P40261 | 2/20 | 0.72 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.72 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.72 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.72 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.71 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.71 |
| ▸ | RNMT | O43148 | 1/20 | 0.71 |
| ▸ | INMT | O95050 | 1/20 | 0.71 |
| ▸ | NSD2 | O96028 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20097060 | 1.00 | EZH2 (1.00) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL4319361 | 1.00 | EZH2 (1.00) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL14174648 | 1.00 | EZH2 (1.00) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL4319379 | 1.00 | EZH2 (1.00) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL19111331 | 0.95 | EZH2 (0.90) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL23120178 | 0.91 | WDR5 (0.93) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL25434994 | 0.90 | EZH2 (0.81) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL19111319 | 0.90 | EZH2 (0.81) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL23120131 | 0.89 | SMYD3 (0.87) | EZH2SMYD3SETD2WDR5KMT2A | |
| SCHEMBL13986292 | 0.89 | SMYD3 (1.00) | EZH2SMYD3SETD2WDR5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090047214-A1 | Novel methylation marker | ONCOMETHYLOME SCIENCES S.A. | 2009-02-19 | — | — | US | claimed |
| US-11987848-B2 | Fecal sample processing and analysis comprising detection of blood | EXACT SCIENCES CORPORATION (US) | 2024-05-21 | — | — | US | disclosed |
| US-11970746-B2 | Fecal sample processing and analysis comprising detection of blood | EXACT SCIENCES CORPORATION (US) | 2024-04-30 | — | — | US | disclosed |
| US-11845991-B2 | Fecal sample processing and analysis comprising detection of blood | EXACT SCIENCES CORPORATION (US) | 2023-12-19 | — | — | US | disclosed |
| US-20230313317-A1 | FECAL SAMPLE PROCESSING AND ANALYSIS COMPRISING DETECTION OF BLOOD | JPMORGAN CHASE BANK, N.A. | 2023-10-05 | — | — | US | disclosed |
| US-20230272488-A1 | FECAL SAMPLE PROCESSING AND ANALYSIS COMPRISING DETECTION OF BLOOD | JPMORGAN CHASE BANK, N.A. | 2023-08-31 | — | — | US | disclosed |
| US-11634781-B2 | Fecal sample processing and analysis comprising detection of blood | JPMORGAN CHASE BANK, N.A. | 2023-04-25 | — | — | US | disclosed |
| US-20230048152-A1 | FECAL SAMPLE PROCESSING AND ANALYSIS COMPRISING DETECTION OF BLOOD | JPMORGAN CHASE BANK, N.A. | 2023-02-16 | — | — | US | disclosed |
| US-11149317-B2 | Methods for detecting epigenetic modifications | EXACT SCIENCES DEVELOPMENT COMPANY, LLC (US) | 2021-10-19 | — | — | US | disclosed |
| US-10808286-B2 | Methods for detecting epigenetic modifications | EXACT SCIENCES DEVELOPMENT COMPANY, LLC (US) | 2020-10-20 | — | — | US | disclosed |
| WO-2010020787-A1 | DIAGNOSIS AND TREATMENT OF TUMOURS | ONCOMETHYLOME SCIENCES SA (BE) | 2010-02-25 | — | — | WO | disclosed |
| WO-2010004251-A1 | DNA METHYLOMES | ONCOMETHYLOME SCIENCES SA (BE) | 2010-01-14 | — | — | WO | disclosed |
| US-20090275632-A1 | Methods of diagnosis and treatment | ONCOMETHYLOME SCIENCES SA | 2009-11-05 | — | — | US | disclosed |
| EP-2069527-A1 | EPIGENETIC CHANGE IN SELECTED GENES AND CANCER | Oncomethylome Sciences SA (BE) | 2009-06-17 | — | — | EP | disclosed |
| WO-2009071920-A2 | METHODS FOR IDENTIFYING EPIGENETICALLY SILENCED GENES AND NOVEL TUMOUR SUPPRESSOR GENES | ONCOMETHYLOME SCIENCES SA (BE) | 2009-06-11 | — | — | WO | disclosed |
| US-20090093424-A1 | Markers for melanoma | UNIVERSITY COLLEGE DUBLIN | 2009-04-09 | — | — | US | disclosed |
| WO-2009037441-A1 | IMPROVED METHYLATION DETECTION | ONCOMETHYLOME SCIENCES SA (BE) | 2009-03-26 | — | — | WO | disclosed |
| US-20090047214-A1 | Novel methylation marker | ONCOMETHYLOME SCIENCES S.A. | 2009-02-19 | — | — | US | disclosed |
| WO-2008084219-A1 | EPIGENETIC CHANGE IN SELECTED GENES AND CANCER | ONCOMETHYLOME SCIENCES SA (BE) | 2008-07-17 | — | — | WO | disclosed |
| EP-1840227-A1 | Markers for melanoma | UNIVERSITY COLLEGE DUBLIN (IE) | 2007-10-03 | — | — | EP | disclosed |