Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HBB | P68871 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15868578 | 0.89 | MAPT (0.65) | KDM4EMAPTALDH1A1MAPK1MEN1 | |
| SCHEMBL29643189 | 0.89 | MAPT (0.65) | KDM4EMAPTALDH1A1MAPK1MEN1 | |
| SCHEMBL13979310 | 0.83 | KDM4E (0.70) | KDM4EMAPTALDH1A1MAPK1MEN1 | |
| SCHEMBL29963695 | 0.82 | ALDH1A1 (0.75) | KDM4EMAPTALDH1A1MAPK1MEN1 | |
| SCHEMBL151563 | 0.82 | ALDH1A1 (0.75) | KDM4EMAPTALDH1A1MAPK1MEN1 | |
| SCHEMBL29360167 | 0.82 | ALDH1A1 (0.75) | KDM4EMAPTALDH1A1MAPK1MEN1 | |
| SCHEMBL5999686 | 0.81 | KDM4E (0.59) | KDM4EMAPTALDH1A1MAPK1MEN1 | |
| SCHEMBL18121158 | 0.81 | KDM4E (0.68) | KDM4EMAPTALDH1A1MAPK1MEN1 | |
| SCHEMBL12498669 | 0.80 | ALDH1A1 (0.72) | KDM4EMAPTALDH1A1MAPK1MEN1 | |
| SCHEMBL31676670 | 0.80 | ALDH1A1 (0.72) | KDM4EMAPTALDH1A1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |