Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | HBB | P68871 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | RORC | P51449 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 2/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15868578 | 1.00 | MAPT (0.65) | MAPTKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL8134208 | 0.91 | KDM4E (0.57) | MAPTKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL20097163 | 0.89 | KDM4E (0.56) | MAPTKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL13979310 | 0.83 | KDM4E (0.70) | MAPTKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL29360167 | 0.82 | ALDH1A1 (0.75) | MAPTKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL151563 | 0.82 | ALDH1A1 (0.75) | MAPTKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL29963695 | 0.82 | ALDH1A1 (0.75) | MAPTKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL29623057 | 0.82 | PER2 (0.51) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL20631884 | 0.82 | KDM4E (0.50) | MAPTKDM4EMAPK1MEN1KMT2A | |
| SCHEMBL14805532 | 0.81 | MAPT (0.69) | MAPTKDM4EMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206360-B | Carbazole amide derivative or salt thereof, and preparation method and application thereof | 复旦大学 | 2022-05-17 | — | — | CN | disclosed |