Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | GMPS | P49915 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.35 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.32 |
| ▸ | AHCY | P23526 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21311192 | 0.86 | DOT1L (0.37) | ADORA2AGMPSADORA3SLC28A1PI4KA | |
| SCHEMBL21311211 | 0.85 | PNMT (0.36) | ADORA2AGMPSADORA3NNMTPNMT | |
| SCHEMBL20097182 | 0.85 | GMPS (0.35) | ADORA2AGMPSADORA3SLC28A1NNMT | |
| SCHEMBL21311209 | 0.83 | DOT1L (0.38) | GMPSPNMTDOT1L | |
| SCHEMBL21311196 | 0.82 | DOT1L (0.34) | ADORA2AGMPSADORA3SLC28A1NNMT | |
| SCHEMBL21311212 | 0.80 | DOT1L (0.35) | ADORA2AGMPSADORA3SLC28A1NNMT | |
| SCHEMBL21311199 | 0.79 | GMPS (0.35) | ADORA2AGMPSADORA3SLC28A1NNMT | |
| SCHEMBL21311465 | 0.79 | NNMT (0.54) | ADORA2AADORA3SLC28A1NNMTPI4KA | |
| SCHEMBL21311390 | 0.78 | DOT1L (0.34) | ADORA2AGMPSADORA3SLC28A1NNMT | |
| SCHEMBL21311388 | 0.77 | DOT1L (0.41) | ADORA2AGMPSADORA3SLC28A1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |