Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 19/20 | 0.59 |
| ▸ | WNT1 | P04628 | 18/20 | 0.59 |
| ▸ | CLK2 | P49760 | 6/20 | 0.54 |
| ▸ | CLK3 | P49761 | 6/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14792592 | 0.89 | DYRK1A (0.73) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL14792533 | 0.88 | DYRK1A (0.74) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL20097131 | 0.86 | DYRK1A (0.59) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL20097416 | 0.86 | WNT1 (0.62) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL20097302 | 0.85 | DYRK1A (0.61) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL20097436 | 0.85 | DYRK1A (0.80) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL20097154 | 0.84 | DYRK1A (0.81) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL20097419 | 0.83 | DYRK1A (0.65) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL23889879 | 0.82 | WNT1 (0.58) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL20097171 | 0.82 | DYRK1A (0.61) | DYRK1AWNT1CLK2CLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075858-A1 | METHODS OF USING INDAZOLE-3-CARBOXAMIDES AND THEIR USE AS WNT/B-CATENIN SIGNALING PATHWAY INHIBITORS | SAMUMED, LLC (US) | 2018-04-26 | — | — | WO | disclosed |