SCHEMBL20097358

SCHEMBL20097358

Cc1cc2ccc(C3CCC(C4CCC(C)CC4)CC3)c(F)c2c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 1/20 0.32
TLR8 Q9NR97 1/20 0.32
TLR7 Q9NYK1 1/20 0.32
NOTUM Q6P988 1/20 0.31
CHRNA7 P36544 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13760083 0.89
SCHEMBL13760084 0.84 ESR2 (0.31)
SCHEMBL803461 0.83
SCHEMBL17997296 0.83 OPRL1 (0.38)
SCHEMBL172451 0.81 ESR2 (0.34) NOTUM
SCHEMBL19160767 0.80
SCHEMBL8932574 0.79 PSMB5 (0.32) TLR9TLR8TLR7
SCHEMBL803460 0.78 ESR2 (0.31)
SCHEMBL12205179 0.78 ESR2 (0.31) NOTUM
SCHEMBL739170 0.78 ESR2 (0.39) NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3670503-B1 COMPOUND, LIQUID CRYSTAL MEDIUM CONTAINING SAME, AND USE THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO LTD (CN) 2023-10-18 EP disclosed
US-11208395-B2 Compound, liquid crystal medium containing the compound and application thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2021-12-28 US disclosed
EP-3670503-A1 COMPOUND, LIQUID CRYSTAL MEDIUM CONTAINING SAME, AND USE THEREOF Shijiazhuang Chengzhi Yonghua Display Material Co., Ltd. (CN) 2020-06-24 EP disclosed
US-20190345129-A1 COMPOUND, LIQUID CRYSTAL MEDIUM CONTAINING THE COMPOUND AND APPLICATION THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2019-11-14 US disclosed
US-10351773-B2 Liquid crystal compounds of cycloalkyl-containing dibenzofuran derivatives, preparation method therefor and use thereof Shijiazhuang Chengzhi Yonghua Display Material Co., Ltd (CN) 2019-07-16 US disclosed
US-20180112132-A1 LIQUID CRYSTAL COMPOUNDS OF CYCLOALKYL-CONTAINING DIBENZOFURAN DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO.,LTD (CN) 2018-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180112132-A1 LIQUID CRYSTAL COMPOUNDS OF CYCLOALKYL-CONTAINING DIBENZOFURAN DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF CYP4F11, WASF2, NOTUM TLR9 4843/4885TLR8 3879/4885TLR7 3856/4885
US-20190345129-A1 COMPOUND, LIQUID CRYSTAL MEDIUM CONTAINING THE COMPOUND AND APPLICATION THEREOF ABCG2, TPST2, TST TLR9 1466/4885TLR8 3582/4885TLR7 1117/4885
US-11208395-B2 Compound, liquid crystal medium containing the compound and application thereof TST, TPST2, ABCG2 TLR9 1337/4885TLR8 3459/4885TLR7 986/4885
US-10351773-B2 Liquid crystal compounds of cycloalkyl-containing dibenzofuran derivatives, preparation method therefor and use thereof CYP4F11, WASF2, NOTUM TLR9 4843/4885TLR8 3879/4885TLR7 3856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.