Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17841604 | 0.84 | HPGD (0.55) | HPGDTSHRALDH1A1GAAMAPT | |
| SCHEMBL26140049 | 0.78 | HPGD (0.48) | HPGDTSHRALDH1A1GAAMAPT | |
| SCHEMBL23948608 | 0.78 | UHRF1 (0.52) | TSHRTDP1UHRF1KMT2A | |
| SCHEMBL25958653 | 0.76 | ALDH1A1 (0.42) | HPGDTSHRALDH1A1GAAMAPT | |
| SCHEMBL25521952 | 0.74 | UHRF1 (0.52) | HPGDTSHRALDH1A1GAAMAPT | |
| SCHEMBL12384971 | 0.74 | UHRF1 (0.52) | TSHRALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL25958444 | 0.74 | CNR1 (0.43) | HPGDALDH1A1GAAMAPTTDP1 | |
| SCHEMBL22738611 | 0.74 | HRH3 (0.57) | NPC1RAB9A | |
| SCHEMBL12442637 | 0.73 | HPGD (0.62) | HPGDALDH1A1GAAMAPTTDP1 | |
| SCHEMBL29944223 | 0.73 | HPGD (0.62) | HPGDALDH1A1GAAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075858-A1 | METHODS OF USING INDAZOLE-3-CARBOXAMIDES AND THEIR USE AS WNT/B-CATENIN SIGNALING PATHWAY INHIBITORS | SAMUMED, LLC (US) | 2018-04-26 | — | — | WO | disclosed |