Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.52 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | NNMT | P40261 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30625387 | 0.85 | NOS3 (0.48) | SIRT6LCKNNMTADORA3TSHR | |
| SCHEMBL25521952 | 0.84 | UHRF1 (0.52) | UHRF1NNMTTSHRGABRPGABRD | |
| SCHEMBL12384971 | 0.84 | UHRF1 (0.52) | UHRF1TSHRGABRPGABRDGABRA1 | |
| SCHEMBL20652740 | 0.84 | SIRT6 (0.43) | UHRF1SIRT6LCKNNMTADORA3 | |
| SCHEMBL3120938 | 0.82 | TSHR (0.42) | SIRT6LCKNNMTADORA3TSHR | |
| SCHEMBL4807973 | 0.79 | MAPK1 (0.47) | UHRF1LCKGABRPGABRDGABRA1 | |
| SCHEMBL30992044 | 0.79 | UHRF1 (0.47) | UHRF1NNMTTSHRGABRPGABRD | |
| SCHEMBL23618778 | 0.79 | UHRF1 (0.47) | UHRF1NNMTTSHRGABRPGABRD | |
| SCHEMBL30992777 | 0.79 | UHRF1 (0.47) | UHRF1TSHRGABRPGABRDGABRA1 | |
| SCHEMBL16318634 | 0.78 | KDM4E (0.43) | SIRT6LCKNNMTADORA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4137491-A1 | IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE | Chengdu Baiyu Pharmaceutical Co., Ltd. (CN) | 2023-02-22 | — | — | EP | disclosed |
| WO-2021209055-A1 | IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2021-10-21 | — | — | WO | disclosed |