Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 7/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.32 |
| ▸ | PDE4A | P27815 | 5/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | FURIN | P09958 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20090389 | 0.78 | ALOX5 (0.35) | — | |
| SCHEMBL21655143 | 0.76 | GABRA1 (0.35) | PDE4DPDE4BPDE4APDE4CFFAR4 | |
| SCHEMBL25565491 | 0.75 | PDE4A (0.30) | PDE4A | |
| SCHEMBL29150470 | 0.75 | PDE4D (0.35) | PDE4DPDE4BPDE4APDE4CF2 | |
| SCHEMBL25565394 | 0.74 | FFAR4 (0.32) | FFAR4 | |
| SCHEMBL18133395 | 0.74 | MPL (0.34) | — | |
| SCHEMBL20090376 | 0.73 | FURIN (0.35) | PDE4DPDE4BPDE4APDE4CFURIN | |
| SCHEMBL16923207 | 0.72 | MCHR1 (0.40) | F2F10PLGPLAUPLAT | |
| SCHEMBL16923010 | 0.72 | MCHR1 (0.40) | F2F10PLGPLAUPLAT | |
| SCHEMBL25565488 | 0.72 | PDE4A (0.33) | PDE4DPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351773-B2 | Liquid crystal compounds of cycloalkyl-containing dibenzofuran derivatives, preparation method therefor and use thereof | Shijiazhuang Chengzhi Yonghua Display Material Co., Ltd (CN) | 2019-07-16 | — | — | US | disclosed |
| US-20180112132-A1 | LIQUID CRYSTAL COMPOUNDS OF CYCLOALKYL-CONTAINING DIBENZOFURAN DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO.,LTD (CN) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180112132-A1 | LIQUID CRYSTAL COMPOUNDS OF CYCLOALKYL-CONTAINING DIBENZOFURAN DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | CYP4F11, WASF2, NOTUM | PDE4D 2304/4885PDE4B 2526/4885PDE4A 3821/4885 |
| US-10351773-B2 | Liquid crystal compounds of cycloalkyl-containing dibenzofuran derivatives, preparation method therefor and use thereof | CYP4F11, WASF2, NOTUM | PDE4D 2304/4885PDE4B 2526/4885PDE4A 3821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.