Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18994197 | 1.00 | LMNA (0.61) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL16745479 | 1.00 | LMNA (0.61) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL17775556 | 1.00 | LMNA (0.61) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL16745470 | 1.00 | LMNA (0.61) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL15895211 | 1.00 | LMNA (0.61) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL23250849 | 1.00 | LMNA (0.61) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL16745469 | 1.00 | LMNA (0.61) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL14147723 | 1.00 | LMNA (0.61) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL28495296 | 0.97 | TDP1 (0.63) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL28495295 | 0.97 | TDP1 (0.63) | LMNAL3MBTL1TDP1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024023138-A2 | CA-IX TARGETING FLUORESCENT PROBES | BRACCO IMAGING SPA (IT) | 2024-02-01 | — | — | WO | disclosed |
| US-9957238-B2 | Arylalkyl-and aryloxyalkyl-substituted epithelial sodium channel blocking compounds | PARION SCIENCES, INC. (US) | 2018-05-01 | — | — | US | disclosed |