SCHEMBL15895211

SCHEMBL15895211

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nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
TDP1 Q9NUW8 2/20 0.58
KDM4E B2RXH2 2/20 0.48
PDE4A P27815 1/20 0.42
TSHR P16473 2/20 0.42
USP2 O75604 1/20 0.39
SLCO1B1 Q9Y6L6 1/20 0.39
TOP1 P11387 1/20 0.34
MGAM O43451 2/20 0.32
MAPT P10636 1/20 0.31
ALDH1A1 P00352 2/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18994197 1.00 LMNA (0.61) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL16745479 1.00 LMNA (0.61) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL20097499 1.00 LMNA (0.61) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL17775556 1.00 LMNA (0.61) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL16745470 1.00 LMNA (0.61) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL23250849 1.00 LMNA (0.61) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL16745469 1.00 LMNA (0.61) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL14147723 1.00 LMNA (0.61) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL28495296 0.97 TDP1 (0.63) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL28495295 0.97 TDP1 (0.63) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9920082-B2 Water-soluble complexing agents and corresponding lanthanide complexes CISBO BIOASSAYS (FR) 2018-03-20 US disclosed
US-20150361116-A1 NOVEL WATER-SOLUBLE COMPLEXING AGENTS AND CORRESPONDING LANTHANIDE COMPLEXES CISBIO BIOASSAYS (FR) 2015-12-17 US disclosed
WO-2014111661-A1 NOVEL WATER-SOLUBLE COMPLEXING AGENTS AND CORRESPONDING LANTHANIDE COMPLEXES CISBIO BIOASSAYS (FR) 2014-07-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150361116-A1 NOVEL WATER-SOLUBLE COMPLEXING AGENTS AND CORRESPONDING LANTHANIDE COMPLEXES RCC1, CLIC1, RCC2 LMNA 381/4885L3MBTL1 2133/4885TDP1 462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.