Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2137893 | 0.85 | ALDH1A1 (0.68) | ALDH1A1KDM4ETSHRMAPTMAPK1 | |
| SCHEMBL23188192 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KDM4ETSHRMAPTMAPK1 | |
| SCHEMBL9221205 | 0.83 | ALDH1A1 (0.65) | ALDH1A1KDM4ETSHRMAPTMAPK1 | |
| SCHEMBL2930129 | 0.82 | ALDH1A1 (0.72) | ALDH1A1KDM4ETSHRMAPTMAPK1 | |
| SCHEMBL24280301 | 0.82 | ALDH1A1 (0.71) | ALDH1A1KDM4ETSHRMAPTMAPK1 | |
| SCHEMBL17485677 | 0.82 | KDM4E (0.74) | ALDH1A1KDM4ETSHRMAPTMAPK1 | |
| SCHEMBL26757990 | 0.81 | ALDH1A1 (0.63) | ALDH1A1KDM4ETSHRMAPTMAPK1 | |
| SCHEMBL23135514 | 0.81 | ALDH1A1 (0.72) | ALDH1A1KDM4ETSHRMAPTMAPK1 | |
| SCHEMBL1331974 | 0.80 | CYP1A2 (0.71) | ALDH1A1KDM4ETSHRMAPTMAPK1 | |
| SCHEMBL1333260 | 0.80 | CYP1A2 (0.71) | ALDH1A1KDM4ETSHRMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9956207-B2 | Antifungal compounds | AMPLYX PHARMACEUTICALS, INC. (US) | 2018-05-01 | — | — | US | disclosed |