Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733243 | 0.87 | GRIN2B (0.57) | KDM4EALDH1A1NPSR1SMN1; SMN2GRIN2B | |
| SCHEMBL8263854 | 0.85 | ALDH1A1 (0.55) | KDM4EALDH1A1NPSR1SMN1; SMN2GRIN2B | |
| SCHEMBL13150170 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1MAPTTSHRNPSR1 | |
| SCHEMBL23301332 | 0.82 | FAAH (0.61) | KDM4EALDH1A1NPSR1SMN1; SMN2GRIN2B | |
| SCHEMBL20097550 | 0.82 | ALDH1A1 (0.73) | KDM4EALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL2930129 | 0.81 | ALDH1A1 (0.72) | KDM4EALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL379160 | 0.81 | MEN1 (0.76) | ALDH1A1TSHRNPSR1SMN1; SMN2GRIN2B | |
| SCHEMBL4814264 | 0.81 | MEN1 (0.76) | ALDH1A1TSHRNPSR1SMN1; SMN2GRIN2B | |
| SCHEMBL3970912 | 0.81 | MEN1 (0.76) | ALDH1A1TSHRNPSR1SMN1; SMN2GRIN2B | |
| SCHEMBL7393652 | 0.81 | MEN1 (0.76) | ALDH1A1TSHRNPSR1SMN1; SMN2GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170210714-A1 | MACROCYCLIC COMPLEXES, THEIR PROCESS OF PREPARATION AND USE AS PET IMAGING AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2017-07-27 | — | — | US | disclosed |
| US-20170210714-A1 | MACROCYCLIC COMPLEXES, THEIR PROCESS OF PREPARATION AND USE AS PET IMAGING AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2017-07-27 | — | — | US | disclosed |
| WO-2016016272-A1 | MACROCYCLIC COMPLEXES, THEIR PROCESS OF PREPARATION AND USE AS PET IMAGING AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2016-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210714-A1 | MACROCYCLIC COMPLEXES, THEIR PROCESS OF PREPARATION AND USE AS PET IMAGING AGENTS | MPI, PAICS, TFEB | KDM4E 3440/4885ALDH1A1 1961/4885MAPT 1103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.