Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 18/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.44 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14756691 | 1.00 | PSMB5 (0.54) | PSMB5PSMB1PSMB2TACR1 | |
| SCHEMBL14756681 | 1.00 | PSMB5 (0.54) | PSMB5PSMB1PSMB2TACR1 | |
| SCHEMBL16024731 | 0.91 | PSMB5 (0.55) | PSMB5PSMB1PSMB2 | |
| SCHEMBL16024773 | 0.91 | PSMB5 (0.55) | PSMB5PSMB1PSMB2 | |
| SCHEMBL24091270 | 0.89 | PSMB5 (0.54) | PSMB5PSMB1PSMB2 | |
| SCHEMBL24091220 | 0.85 | PSMB5 (0.49) | PSMB5PSMB1PSMB2 | |
| SCHEMBL16024753 | 0.80 | PSMB5 (0.46) | PSMB5TACR1 | |
| Hydrochloric Acid SCHEMBL31238304 | 0.78 | PSMB5 (0.68) | PSMB5PSMB1PSMB2 | |
| SCHEMBL1432145 | 0.77 | TACR1 (0.46) | TACR1 | |
| SCHEMBL26211758 | 0.76 | OPRD1 (0.49) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9956297-B2 | FAP-activated proteasome inhibitors for treating solid tumors | TRUSTEES OF TUFTS COLLEGE (US) | 2018-05-01 | — | — | US | disclosed |