Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 8/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | CCKBR | P32239 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.41 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26211704 | 0.91 | OPRD1 (0.45) | OPRD1OPRM1TACR1CCKBRAKT1 | |
| SCHEMBL26211725 | 0.80 | TACR1 (0.55) | OPRM1TACR1PSMB9 | |
| SCHEMBL23381319 | 0.80 | TACR1 (0.55) | OPRM1TACR1PSMB9 | |
| SCHEMBL26211765 | 0.79 | OPRD1 (0.49) | OPRD1OPRM1 | |
| SCHEMBL1432145 | 0.76 | TACR1 (0.46) | OPRD1TACR1 | |
| SCHEMBL20097951 | 0.76 | PSMB5 (0.54) | TACR1 | |
| SCHEMBL14756681 | 0.76 | PSMB5 (0.54) | TACR1 | |
| SCHEMBL14756691 | 0.76 | PSMB5 (0.54) | TACR1 | |
| SCHEMBL26211712 | 0.74 | OPRD1 (0.45) | OPRD1PSMB9 | |
| SCHEMBL23381127 | 0.73 | TACR1 (0.54) | OPRM1TACR1PSMB9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746126-B2 | Bicyclic peptide ligands with detectable moieties and uses thereof | Bicyclerd Limited (GB) | 2023-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746126-B2 | Bicyclic peptide ligands with detectable moieties and uses thereof | VIP, NGLY1, GRPR | OPRD1 3256/4885OPRM1 1992/4885TACR1 190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.