SCHEMBL20097979

SCHEMBL20097979

CN1C(=O)c2ccc3c4cccc5c(I)ccc(c6ccc(c2c36)C1=O)c54

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.51
KDM4E B2RXH2 3/20 0.51
ALDH1A1 P00352 3/20 0.51
USP2 O75604 2/20 0.51
KEAP1 Q14145 2/20 0.51
NFE2L2 Q16236 2/20 0.51
ATM Q13315 1/20 0.51
HPGD P15428 1/20 0.51
POLB P06746 2/20 0.49
PRMT1 Q99873 1/20 0.49
TERT O14746 4/20 0.43
STAT3 P40763 1/20 0.41
HIF1A Q16665 1/20 0.41
TYMS P04818 2/20 0.38
CASP3 P42574 1/20 0.37
PKM P14618 1/20 0.37
SIRT2 Q8IXJ6 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
APP P05067 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12869514 0.86 KMT2A (0.57) KMT2AMEN1KDM4EALDH1A1USP2
SCHEMBL12869518 0.83 KMT2A (0.63) KMT2AMEN1KDM4EALDH1A1USP2
SCHEMBL710594 0.82 TERT (0.56) KMT2AMEN1KDM4EALDH1A1USP2
SCHEMBL29355182 0.82 TERT (0.56) KMT2AMEN1KDM4EALDH1A1USP2
SCHEMBL9968958 0.82 TERT (0.56) KMT2AMEN1KDM4EALDH1A1USP2
SCHEMBL12170761 0.82 TERT (0.56) KMT2AMEN1KDM4EALDH1A1USP2
SCHEMBL9968962 0.82 TERT (0.56) KMT2AMEN1KDM4EALDH1A1USP2
SCHEMBL12856931 0.82 MEN1 (0.53) KMT2AMEN1KDM4EALDH1A1USP2
SCHEMBL9968959 0.82 MEN1 (0.53) KMT2AMEN1KDM4EALDH1A1USP2
SCHEMBL4857545 0.81 KMT2A (0.56) KMT2AMEN1KDM4EALDH1A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9959982-B2 Photoelectric conversion element and method for producing the same Konica Minolta, Inc. (JP) 2018-05-01 US disclosed