Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29355182 | 1.00 | TERT (0.56) | TERTMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL710594 | 1.00 | TERT (0.56) | TERTMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL12170761 | 1.00 | TERT (0.56) | TERTMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL9968958 | 1.00 | TERT (0.56) | TERTMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL30937815 | 0.90 | MEN1 (0.55) | TERTMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL127059 | 0.90 | MEN1 (0.55) | TERTMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL12748863 | 0.90 | TERT (0.49) | TERTMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL12449220 | 0.90 | MEN1 (0.54) | TERTMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL18500360 | 0.90 | TERT (0.49) | TERTMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL9968961 | 0.90 | TERT (0.49) | TERTMEN1KMT2AALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202994-B2 | Pentarylene- and hexarylenetetracarboximides and preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 2012-06-19 | — | — | US | disclosed |
| US-8052899-B2 | Heptarylene-and octarylenetetracarboximides and preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 2011-11-08 | — | — | US | disclosed |
| US-20100072438-A1 | HEPTARYLENE-AND OCTARYLENETETRACARBOXIMIDES AND PREPARATION THEREOF | BASF SE (DE) | 2010-03-25 | — | — | US | disclosed |
| US-20100059716-A1 | PENTARYLENE-AND HEXARYLENETETRACARBOXIMIDES AND PREPARATION THEREOF | BASF SE (DE) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100072438-A1 | HEPTARYLENE-AND OCTARYLENETETRACARBOXIMIDES AND PREPARATION THEREOF | CYP4A22, CYP2C9, CYP4F11 | TERT 1731/4885MEN1 685/4885KMT2A 4211/4885 |
| US-20100059716-A1 | PENTARYLENE-AND HEXARYLENETETRACARBOXIMIDES AND PREPARATION THEREOF | CYP2C9, PNPO, CYP3A43 | TERT 1767/4885MEN1 1512/4885KMT2A 3106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.