SCHEMBL200982

SCHEMBL200982

BrCCn1cccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL31039724 0.98
SCHEMBL4116864 0.86
SCHEMBL9486879 0.84 DAO (0.38)
SCHEMBL5713341 0.84 DAO (0.50)
SCHEMBL7350459 0.82 DAO (0.37)
SCHEMBL18543119 0.82 DAO (0.37)
SCHEMBL7100687 0.79 DAO (0.43)
SCHEMBL859075 0.79
SCHEMBL348081 0.78 ALDH1A1 (0.43)
SCHEMBL33257 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113582928-A Amino-phenol-oxygen-group zinc complex containing (substituted) pyrazole ring and preparation method and application thereof 华东理工大学 2021-11-02 CN claimed
US-20260116881-A1 KIF MODULATOR COMPOUNDS AND METHODS OF USE IAMBIC THERAPEUTICS INC (US) 2026-04-30 US disclosed
EP-4630417-A1 NOVEL COMPOUNDS AS MODULATORS OF NLRP3 INHIBITION F. Hoffmann-La Roche AG (CH) 2025-10-15 EP disclosed
US-12440484-B2 1,3,4-oxadiazole homophthalimide derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same CHONG KUN DANG PHARMACEUTICAL CORPORATION (KR) 2025-10-14 US disclosed
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 US disclosed
WO-2025072539-A1 AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF PLIANT THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed
WO-2024217515-A1 HETEROCYCLIC RING-SUBSTITUTED AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海复宏汉霖生物技术股份有限公司 2024-10-24 WO disclosed
CN-113874369-B 1,3, 4-Oxadiazole homophthalimide derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions containing the same 株式会社 钟根堂 2024-08-27 CN disclosed
CN-112839942-B 1,3, 4-Oxadiazole derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions containing the same 株式会社 钟根堂 2024-08-23 CN disclosed
WO-2024121086-A1 NOVEL COMPOUNDS AS MODULATORS OF NLRP3 INHIBITION F. HOFFMANN-LA ROCHE AG (CH) 2024-06-13 WO disclosed
WO-2008059368-A2 FUSED 2-AMINO PYRIMIDINE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCER PFIZER PRODUCTS INC. (US) 2008-05-22 WO disclosed
WO-2008006479-A1 2-(HETEROARYL) ALKYL INDAZOLE 6-PHENYL AND THIENYL METHYL AMIDE AS THROMBIN INHIBITORS BAYER HEALTHCARE AG (DE) 2008-01-17 WO disclosed
WO-2007107758-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2007-09-27 WO disclosed
US-20060198785-A1 Bifunctional tridentate pyrazolyl containing ligands for re and tc tricarbonyl complexes MALLINCKRODT HOSPITAL PRODUCTS IP UNLIMITED COMPANY (F/K/A MALLINCKRODT HOSPITAL PRODUCTS IP LIMITED) (IE) 2006-09-07 US disclosed
CN-1774268-A Bifunctional tridentate pyrazolyl containing ligands for rhenium and technetium tricarbonyl complexes MALLINCKRODT INC (US) 2006-05-17 CN disclosed
EP-1644050-A1 BIFUNCTIONAL TRIDENTATE PYRAZOLYL CONTAINING LIGANDS FOR RE, TC AND MN TRICARBONYL COMPLEXES Mallinckrodt Inc. (US) 2006-04-12 EP disclosed
EP-1529537-A1 Bifunctional tridentate pyrazolyl containing ligands for RE, TC and MN tricarbonyl complexes Mallinckrodt International Corporation (US) 2005-05-11 EP disclosed
WO-2004091669-A1 BIFUNCTIONAL TRIDENTATE PYRAZOLYL CONTAINING LIGANDS FOR RE AND TC TRICARBONYL COMPLEXES MALLINCKRODT INC. (US) 2004-10-28 WO disclosed
EP-0790241-A1 COMPLEXONES WITH THE STRUCTURE OF N-2-(AZOL-1(2)-YL)ETHYLIMINODIACETIC ACIDS, SYNTHESIS, ANALYTICAL STUDY AND BIOLOGICAL APPLICATIONS UNIVERSIDAD NACIONAL DE EDUCACION A DISTANCIA (ES) 1997-08-20 EP disclosed
CN-86108691-A Pyrazole oxime derivatives, process for their preparation and their use NIHON NOHYAKU CO LTD (JP) 1988-01-20 CN disclosed