Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 12/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18499535 | 0.73 | BCAT2 (0.56) | NPC1RAB9APKMCYP11B2CYP11B1 | |
| SCHEMBL20099012 | 0.68 | FFAR4 (0.52) | FFAR4FFAR1 | |
| SCHEMBL20246096 | 0.67 | FFAR4 (0.54) | FFAR4FFAR1 | |
| SCHEMBL13113238 | 0.65 | NPC1 (0.61) | NPC1RAB9APKMCYP11B2 | |
| SCHEMBL2437598 | 0.64 | CASP1 (0.49) | CYP11B2CYP11B1CASP1CASP7HSD17B10 | |
| SCHEMBL4144745 | 0.63 | FFAR4 (0.55) | FFAR4FFAR1 | |
| SCHEMBL29630916 | 0.62 | NPC1 (0.65) | NPC1RAB9APKMCYP11B2 | |
| SCHEMBL10085509 | 0.61 | NPC1 (0.69) | NPC1RAB9APKMCYP11B2CASP1 | |
| SCHEMBL1853918 | 0.60 | HSD17B10 (0.52) | PKMCASP1CASP7HSD17B10 | |
| SCHEMBL1725142 | 0.60 | HSD17B10 (0.52) | PKMCASP1CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957264-B2 | Geminally substituted cyanoethylpyrazolo pyridones as Janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2018-05-01 | — | — | US | disclosed |