SCHEMBL20099129

SCHEMBL20099129

C=Nc1nccc(C)c1/C=C\C

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.31
CCR5 P51681 1/20 0.31
CCR8 P51685 1/20 0.31
NOS3 P29474 2/20 0.31
NOS2 P35228 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25680180 0.82 CCR1 (0.31) CCR1CCR5CCR8NOS3NOS2
SCHEMBL20203156 0.80 CCR1 (0.32) CCR1CCR5CCR8NOS3NOS2
SCHEMBL21364111 0.78
SCHEMBL21649880 0.77 CCR1 (0.38) CCR1CCR5CCR8NOS3NOS2
SCHEMBL22568135 0.73 CCR1 (0.35) CCR1CCR5CCR8NOS3NOS2
SCHEMBL24493035 0.72 NOS2 (0.52) CCR1CCR5CCR8NOS3NOS2
SCHEMBL21322469 0.69
SCHEMBL9974577 0.69
SCHEMBL18760647 0.69 PLAU (0.33)
SCHEMBL25463256 0.69 CCR1 (0.32) CCR1CCR5CCR8NOS3NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9960294-B2 Highly fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2018-05-01 US disclosed