Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20100181 | 1.00 | ALDH1A1 (0.53) | ALDH1A1GAATSHRL3MBTL1LMNA | |
| SCHEMBL21842269 | 1.00 | ALDH1A1 (0.53) | ALDH1A1GAATSHRL3MBTL1LMNA | |
| SCHEMBL12543513 | 0.92 | ALDH1A1 (0.61) | ALDH1A1GAATSHRL3MBTL1LMNA | |
| SCHEMBL12437114 | 0.84 | KMT2A (0.48) | ALDH1A1GAATSHRL3MBTL1LMNA | |
| SCHEMBL23839910 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPK1ALDH1A2ALDH2ALDH1A3 | |
| SCHEMBL23188735 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPK1ALDH1A2ALDH2ALDH1A3 | |
| SCHEMBL17777241 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPK1ALDH1A2ALDH2ALDH1A3 | |
| SCHEMBL23442889 | 0.83 | TSHR (0.48) | ALDH1A1GAATSHRMAPK1ALDH1A2 | |
| SCHEMBL18596695 | 0.83 | ALDH1A1 (0.54) | ALDH1A1GAATSHRL3MBTL1LMNA | |
| SCHEMBL23136899 | 0.83 | TSHR (0.48) | ALDH1A1GAATSHRMAPK1ALDH1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4144738-A1 | COELENTERAZINE ANALOGUES TETHERED TO ENERGY ACCEPTORS | Promega Corporation (US) | 2023-03-08 | — | — | EP | disclosed |
| US-20180119200-A1 | COELENTERAZINE ANALOGUES TETHERED TO ENERGY ACCEPTORS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180119200-A1 | COELENTERAZINE ANALOGUES TETHERED TO ENERGY ACCEPTORS | GLB1, SI, AADAC | ALDH1A1 2800/4885GAA 771/4885TSHR 3004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.