Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20100440 | 0.88 | ALDH1A1 (0.45) | TDP1ALDH1A1LMNARAB9AHDAC1 | |
| SCHEMBL20100442 | 0.84 | ATM (0.55) | TDP1ALDH1A1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL20100374 | 0.76 | HDAC1 (0.56) | ALDH1A1LMNARAB9AHDAC1MAPT | |
| SCHEMBL24241673 | 0.75 | RAB9A (0.57) | TDP1ALDH1A1LMNARAB9AHDAC1 | |
| SCHEMBL28941993 | 0.74 | MAPT (0.50) | TDP1ALDH1A1LMNARAB9AHDAC1 | |
| SCHEMBL24534904 | 0.74 | HDAC1 (0.55) | TDP1ALDH1A1LMNARAB9AHDAC1 | |
| SCHEMBL20100388 | 0.74 | HDAC1 (0.44) | ALDH1A1LMNARAB9AHDAC1MAPT | |
| SCHEMBL10234475 | 0.73 | SMN1; SMN2 (0.48) | ALDH1A1LMNARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL14867062 | 0.73 | MEN1 (0.50) | ALDH1A1RAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL5690964 | 0.73 | HDAC1 (0.72) | ALDH1A1LMNARAB9AHDAC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10042259-B2 | Topcoat compositions and pattern-forming methods | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2018-08-07 | — | — | US | disclosed |
| US-20180118970-A1 | TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS | ROHM AND HAAS ELECTRONIC MATERIALS LLC | 2018-05-03 | — | — | US | disclosed |