Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31304938 | 0.78 | MAPT (0.41) | MAPTKDM4EGAAGLACA12 | |
| SCHEMBL10405006 | 0.73 | KDM4E (0.45) | MAPTKDM4EGAAGLACA12 | |
| SCHEMBL20511627 | 0.70 | CA12 (0.47) | MAPTKDM4EGAAGLACA12 | |
| SCHEMBL522786 | 0.70 | CA12 (0.47) | MAPTKDM4EGAAGLACA12 | |
| SCHEMBL10465981 | 0.69 | KDM4E (0.53) | MAPTKDM4EGAAGLACA12 | |
| SCHEMBL829753 | 0.69 | CA12 (0.54) | MAPTKDM4EGAAGLACA12 | |
| SCHEMBL410165 | 0.67 | ALPL (0.45) | MAPTKDM4EGAAGLACA12 | |
| SCHEMBL522062 | 0.66 | CA12 (0.52) | MAPTKDM4EGAAGLACA12 | |
| SCHEMBL1994444 | 0.65 | MAPT (0.43) | MAPTKDM4EGAAGLACA12 | |
| SCHEMBL69740 | 0.65 | NR4A2 (0.48) | MAPTKDM4EGAAGLACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018079628-A1 | PYRROLE DERIVATIVE WITH FUSED RING AND PHARMACEUTICAL USE THEREOF | 大日本住友製薬株式会社 | 2018-05-03 | — | — | WO | disclosed |