SCHEMBL20100975

SCHEMBL20100975

CCC(=O)N1C=CCC1=O

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.34
LMNA P02545 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
BLM P54132 1/20 0.33
CES1 P23141 1/20 0.32
ELANE P08246 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11052846 0.77
Acetic Acid SCHEMBL9142827 0.73 NOTUM (0.31)
SCHEMBL12649352 0.67
SCHEMBL7171232 0.65 CES1 (0.33) LMNAKDM4EHTTSMN1; SMN2BLM
SCHEMBL2377717 0.63 POLB (0.50) POLBLMNAKDM4EHTTSMN1; SMN2
SCHEMBL7737649 0.63 KDM4E (0.44) POLBLMNAKDM4EHTTSMN1; SMN2
SCHEMBL10279873 0.62 LMNA (0.49) LMNA
SCHEMBL762384 0.61
SCHEMBL18116998 0.60 GLA (0.33)
SCHEMBL6959243 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180119063-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 US disclosed
US-20180119069-A1 REACTIVE LEUCO COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME THE PROCTER & GAMBLE COMPANY 2018-05-03 US disclosed
US-20180119062-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 US disclosed
US-20180118948-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS MILLIKEN & COMPANY 2018-05-03 US disclosed
US-20180119064-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 US disclosed